Player - Interceptions
| NameFL | TAbb | PosN | Int | IntY | IntAvg | IntL | IntTDs |
| LaRon Landry | OAK | Strong Safety | 10 | 160 | 16.0 | 64 | 1 |
| Ty Law | GBA | Left CB | 8 | 41 | 5.1 | 15 | 0 |
| Jermaine Phillips | ARI | Strong Safety | 7 | 137 | 19.6 | 69 | 1 |
| Marlon McCree | DAL | Free Safety | 7 | 109 | 15.6 | 50 | 1 |
| Brodney Pool | CLE | Free Safety | 7 | 95 | 13.6 | 25 | 0 |
| Kerry Rhodes | NYJ | Strong Safety | 7 | 26 | 3.7 | 22 | 0 |
| Nick Harper | IND | Left CB | 6 | 124 | 20.7 | 45 | 2 |
| Vincent Fuller | ARI | 1st Defensive Back | 6 | 119 | 19.8 | 54 | 1 |
| James Sanders | CLE | Free Safety | 6 | 79 | 13.2 | 25 | 0 |
| John Lynch | NEE | Free Safety | 6 | 79 | 13.2 | 22 | 0 |
| Eugene Wilson | PHI | 1st Defensive Back | 6 | 77 | 12.8 | 22 | 0 |
| Josh Bullocks | NYJ | Free Safety | 6 | 69 | 11.5 | 25 | 0 |
| Ed Reed | MIA | Free Safety | 6 | 38 | 6.3 | 13 | 0 |
| Asante Samuel | CLE | Left CB | 5 | 146 | 29.2 | 94 | 1 |
| Tye Hill | CHI | 1st Defensive Back | 5 | 130 | 26.0 | 68 | 1 |
| Patrick Surtain | MIA | Right CB | 5 | 119 | 23.8 | 62 | 1 |
| Champ Bailey | MIA | Left CB | 5 | 118 | 23.6 | 69 | 1 |
| Quentin Jammer | DAL | Left CB | 5 | 73 | 14.6 | 56 | 1 |
| Clinton Hart | GBA | Strong Safety | 5 | 71 | 14.2 | 20 | 0 |
| Victor Hobson | MIN | Right O LB | 5 | 67 | 13.4 | 25 | 0 |
| Michael Lewis | CHI | Strong Safety | 5 | 59 | 11.8 | 25 | 0 |
| Antoine Bethea | BAL | Free Safety | 5 | 58 | 11.6 | 25 | 0 |
| Dre' Bly | BAL | Right CB | 5 | 42 | 8.4 | 13 | 0 |
| Marlin Jackson | DAL | Right CB | 5 | 42 | 8.4 | 20 | 0 |
| Will Allen | SEA | Left CB | 5 | 35 | 7.0 | 13 | 0 |
| Phillip Buchanon | CHI | Right CB | 5 | 13 | 2.6 | 13 | 0 |
| Corey Chavous | BUF | Strong Safety | 4 | 64 | 16.0 | 25 | 0 |
| Eric D. Green | SEA | Right CB | 4 | 56 | 14.0 | 41 | 1 |
| Gibril Wilson | SFR | Free Safety | 4 | 51 | 12.8 | 35 | 1 |
| Cortland Finnegan | SEA | Right CB | 4 | 51 | 12.8 | 25 | 0 |
| DeAngelo Hall | DET | Left CB | 4 | 44 | 11.0 | 20 | 0 |
| Troy Polamalu | STL | Strong Safety | 4 | 44 | 11.0 | 20 | 0 |
| Mark Roman | MIN | Free Safety | 4 | 42 | 10.5 | 20 | 0 |
| Charles Tillman | CLE | Left CB | 4 | 39 | 9.8 | 25 | 0 |
| Fred Bennett | CIN | Right CB | 4 | 38 | 9.5 | 15 | 0 |
| Antonio Cromartie | CHI | Right CB | 4 | 38 | 9.5 | 20 | 0 |
| Chris Harris | DAL | Strong Safety | 4 | 37 | 9.3 | 15 | 1 |
| Deon Grant | BAL | Strong Safety | 4 | 36 | 9.0 | 22 | 0 |
| Leigh Bodden | DET | Right CB | 4 | 35 | 8.8 | 15 | 0 |
| Reed Doughty | NYG | Strong Safety | 4 | 33 | 8.3 | 20 | 0 |
| Brian Dawkins | MIA | Free Safety | 4 | 32 | 8.0 | 15 | 0 |
| Aaron Ross | ARI | Left CB | 4 | 26 | 6.5 | 12 | 0 |
| Nate Clements | BAL | Left CB | 4 | 25 | 6.3 | 13 | 0 |
| Quintin Mikell | PHI | 1st Defensive Back | 4 | 24 | 6.0 | 12 | 0 |
| Mike McKenzie | JAX | Left CB | 4 | 23 | 5.8 | 13 | 0 |
| Lito Sheppard | NYJ | Left CB | 4 | 23 | 5.8 | 13 | 0 |
| Adrian Wilson | JAX | Strong Safety | 4 | 8 | 2.0 | 4 | 0 |
| Roy Williams | BUF | Strong Safety | 4 | 0 | 0.0 | 0 | 0 |
| Sean Considine | CAR | Strong Safety | 3 | 54 | 18.0 | 25 | 0 |
| Fernando Bryant | SDI | Left CB | 3 | 48 | 16.0 | 25 | 0 |
| O.J. Atogwe | IND | Free Safety | 3 | 42 | 14.0 | 22 | 0 |
| Tramon Williams | STL | 1st Defensive Back | 3 | 42 | 14.0 | 25 | 2 |
| Anthony Henry | GBA | Right CB | 3 | 38 | 12.7 | 22 | 0 |
| Chris McAlister | BUF | Left CB | 3 | 36 | 12.0 | 20 | 0 |
| Donte Whitner | SDI | Strong Safety | 3 | 35 | 11.7 | 13 | 0 |
| Al Harris | CIN | Right CB | 3 | 35 | 11.7 | 20 | 0 |
| Lawyer Milloy | CAR | Strong Safety | 3 | 29 | 9.7 | 13 | 0 |
| Ken Hamlin | NYG | Free Safety | 3 | 29 | 9.7 | 13 | 0 |
| Ronald Bartell | SFR | Left CB | 3 | 27 | 9.0 | 15 | 0 |
| Darren Sharper | JAX | Strong Safety | 3 | 24 | 8.0 | 12 | 0 |
| Keith Bulluck | PHI | Right LB | 3 | 23 | 7.7 | 15 | 0 |
| Dunta Robinson | BUF | Left CB | 3 | 16 | 5.3 | 12 | 0 |
| Walt Harris | CAR | Right CB | 3 | 16 | 5.3 | 12 | 0 |
| Tanard Jackson | IND | Free Safety | 3 | 13 | 4.3 | 13 | 0 |
| Sam Madison | GBA | Right CB | 3 | 12 | 4.0 | 12 | 0 |
| Clark Haggans | GBA | Left O LB | 3 | 4 | 1.3 | 4 | 0 |
| Fakhir Brown | IND | Right CB | 3 | 0 | 0.0 | 0 | 0 |
| Darrelle Revis | DET | Left CB | 2 | 115 | 57.5 | 95 | 1 |
| Kawika Mitchell | CHI | Right LB | 2 | 67 | 33.5 | 63 | 1 |
| Donnie Edwards | NEE | Right LB | 2 | 58 | 29.0 | 46 | 1 |
| Nate Webster | PHI | Left LB | 2 | 42 | 21.0 | 22 | 0 |
| Ben Leber | IND | Left LB | 2 | 42 | 21.0 | 22 | 0 |
| Keith Davis | STL | 1st Defensive Back | 2 | 42 | 21.0 | 22 | 0 |
| Brian Williams | HOU | Right CB | 2 | 40 | 20.0 | 25 | 0 |
| Willie McGinest | BAL | Left O LB | 2 | 32 | 16.0 | 20 | 0 |
| Reggie Nelson | SDI | Free Safety | 2 | 32 | 16.0 | 20 | 0 |
| Andre' Goodman | STL | 1st Defensive Back | 2 | 32 | 16.0 | 20 | 0 |
| Brian Russell | HOU | Free Safety | 2 | 26 | 13.0 | 22 | 0 |
| Bryant McFadden | OAK | 1st Defensive Back | 2 | 26 | 13.0 | 22 | 0 |
| Sean Jones | SEA | Strong Safety | 2 | 25 | 12.5 | 25 | 0 |
| Nick Ferguson | MIA | 1st Defensive Back | 2 | 25 | 12.5 | 25 | 0 |
| Kelvin Hayden | SFR | Left CB | 2 | 25 | 12.5 | 25 | 0 |
| Charles Woodson | OAK | Left CB | 2 | 22 | 11.0 | 22 | 0 |
| Ellis Hobbs | PHI | Right CB | 2 | 22 | 11.0 | 22 | 0 |
| Bryan Thomas | DET | Left O LB | 2 | 20 | 10.0 | 20 | 0 |
| Will Witherspoon | NYG | Middle LB | 2 | 17 | 8.5 | 13 | 0 |
| Kevin Dockery | NEE | CB | 2 | 17 | 8.5 | 13 | 0 |
| Jarrad Page | CIN | Free Safety | 2 | 15 | 7.5 | 15 | 0 |
| Sammy Knight | CAR | Strong Safety | 2 | 14 | 7.0 | 10 | 0 |
| Morlon Greenwood | HOU | Right LB | 2 | 14 | 7.0 | 10 | 0 |
| Michael Johnson | ARI | 1st Defensive Back | 2 | 13 | 6.5 | 13 | 0 |
| Marcus Trufant | MIN | Left CB | 2 | 13 | 6.5 | 13 | 0 |
| Derrick Johnson | NYJ | Left LB | 2 | 12 | 6.0 | 12 | 0 |
| Shaun Rogers | OAK | Right Tackle | 2 | 12 | 6.0 | 12 | 0 |
| Shawn Springs | JAX | Left CB | 2 | 10 | 5.0 | 10 | 0 |
| Rashean Mathis | MIN | Left CB | 2 | 10 | 5.0 | 10 | 0 |
| Calvin Lowry | SFR | 1st Defensive Back | 2 | 4 | 2.0 | 4 | 0 |
| Ronde Barber | OAK | Left CB | 2 | 4 | 2.0 | 4 | 0 |
| Drayton Florence | NYG | 1st Defensive Back | 2 | 4 | 2.0 | 4 | 0 |
| Sean Taylor | GBA | Free Safety | 2 | 0 | 0.0 | 0 | 0 |
| Thomas Howard | CLE | Left LB | 1 | 84 | 84.0 | 84 | 1 |
| Angelo Crowell | DET | Left LB | 1 | 43 | 43.0 | 43 | 1 |
| Brian Urlacher | SEA | Middle LB | 1 | 25 | 25.0 | 25 | 0 |
| Hamza Abdullah | CIN | Strong Safety | 1 | 25 | 25.0 | 25 | 0 |
| Richard Marshall | SDI | CB | 1 | 25 | 25.0 | 25 | 0 |
| Fabian Washington | MIA | 1st Defensive Back | 1 | 25 | 25.0 | 25 | 0 |
| Kirk Morrison | SFR | Middle LB | 1 | 25 | 25.0 | 25 | 0 |
| Randall Gay | DET | 1st Defensive Back | 1 | 25 | 25.0 | 25 | 0 |
| Karl Paymah | NEE | 1st Defensive Back | 1 | 25 | 25.0 | 25 | 0 |
| Antonio Pierce | JAX | Middle LB | 1 | 25 | 25.0 | 25 | 0 |
| Terence Newman | CAR | Left CB | 1 | 25 | 25.0 | 25 | 0 |
| Rocky Bernard | HOU | Right Tackle | 1 | 25 | 25.0 | 25 | 0 |
| Calvin Pace | CLE | Left LB | 1 | 22 | 22.0 | 22 | 0 |
| Ken Lucas | PHI | Right CB | 1 | 22 | 22.0 | 22 | 0 |
| Hunter Hillenmeyer | OAK | Left LB | 1 | 22 | 22.0 | 22 | 0 |
| Vince Wilfork | SFR | Nose Tackle | 1 | 21 | 21.0 | 21 | 1 |
| Marcus Stroud | BUF | Left Tackle | 1 | 20 | 20.0 | 20 | 0 |
| Bernard Pollard | NYG | Strong Safety | 1 | 20 | 20.0 | 20 | 0 |
| Demorrio Williams | OAK | Right LB | 1 | 20 | 20.0 | 20 | 0 |
| DeMarcus Ware | DAL | Right O LB | 1 | 20 | 20.0 | 20 | 0 |
| Parys Haralson | STL | Left O LB | 1 | 20 | 20.0 | 20 | 0 |
| Kevin Payne | IND | 1st Defensive Back | 1 | 20 | 20.0 | 20 | 0 |
| Tim Jennings | SFR | 1st Defensive Back | 1 | 15 | 15.0 | 15 | 0 |
| Mike Peterson | GBA | Middle LB | 1 | 15 | 15.0 | 15 | 0 |
| Jimmy F. Williams | SDI | 1st Defensive Back | 1 | 15 | 15.0 | 15 | 0 |
| Chris Canty | CLE | Right End | 1 | 14 | 14.0 | 14 | 1 |
| Gerald Hayes | CHI | Middle LB | 1 | 13 | 13.0 | 13 | 0 |
| Hank Poteat | MIA | Right CB | 1 | 13 | 13.0 | 13 | 0 |
| Anthony Weaver | NEE | Left End | 1 | 12 | 12.0 | 12 | 0 |
| Luis Castillo | BAL | Right End | 1 | 12 | 12.0 | 12 | 0 |
| Thomas Davis | NYG | Left LB | 1 | 12 | 12.0 | 12 | 0 |
| Bob Sanders | MIN | Strong Safety | 1 | 12 | 12.0 | 12 | 0 |
| Rocky McIntosh | NYJ | Right LB | 1 | 12 | 12.0 | 12 | 0 |
| Michael Griffin | CLE | Free Safety | 1 | 12 | 12.0 | 12 | 0 |
| Leroy Hill | SFR | Left LB | 1 | 12 | 12.0 | 12 | 0 |
| Reggie Hayward | SFR | Left End | 1 | 12 | 12.0 | 12 | 0 |
| Shaun Phillips | NEE | Right O LB | 1 | 10 | 10.0 | 10 | 0 |
| Napoleon Harris | NEE | Middle LB | 1 | 10 | 10.0 | 10 | 0 |
| Danieal Manning | CHI | Free Safety | 1 | 10 | 10.0 | 10 | 0 |
| Gerard Warren | ARI | Right Tackle | 1 | 10 | 10.0 | 10 | 0 |
| Chris Gamble | NYG | Left CB | 1 | 10 | 10.0 | 10 | 0 |
| Antrel Rolle | CLE | CB | 1 | 4 | 4.0 | 4 | 0 |
| Aaron Smith | CIN | Left End | 1 | 4 | 4.0 | 4 | 0 |
| Brian Robison | NEE | Def End | 1 | 4 | 4.0 | 4 | 0 |
| Atari Bigby | HOU | Strong Safety | 1 | 4 | 4.0 | 4 | 0 |
| Frank Walker | NYJ | 1st Defensive Back | 1 | 4 | 4.0 | 4 | 0 |
| Ty Warren | GBA | Left End | 1 | 4 | 4.0 | 4 | 0 |
| Mike Vrabel | GBA | Left O LB | 1 | 4 | 4.0 | 4 | 0 |
| Igor Olshansky | CLE | Left End | 1 | 4 | 4.0 | 4 | 0 |
| Ernie Sims | CHI | Right LB | 1 | 4 | 4.0 | 4 | 0 |
| Shaun Ellis | IND | Left End | 1 | 4 | 4.0 | 4 | 0 |
| Jamar Williams | SEA | LB | 1 | 4 | 4.0 | 4 | 0 |
| Brandon McGowan | STL | Strong Safety | 1 | 4 | 4.0 | 4 | 0 |
| Jordan Babineaux | DAL | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Kenoy Kennedy | MIN | Strong Safety | 1 | 0 | 0.0 | 0 | 0 |
| Chris Hope | DAL | Strong Safety | 1 | 0 | 0.0 | 0 | 0 |
| Marvin White | SFR | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Jason Allen | SDI | Free Safety | 1 | 0 | 0.0 | 0 | 0 |
| Chinedum Ndukwe | ARI | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Roderick Hood | JAX | Left CB | 1 | 0 | 0.0 | 0 | 0 |
| Eric Weddle | DET | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Landon Johnson | SFR | Middle LB | 1 | 0 | 0.0 | 0 | 0 |
| Sheldon Brown | PHI | Right CB | 1 | 0 | 0.0 | 0 | 0 |
| Mike Rucker | CAR | Right End | 1 | 0 | 0.0 | 0 | 0 |
| Antoine Winfield | NEE | Left CB | 1 | 0 | 0.0 | 0 | 0 |
| Elvis Dumervil | JAX | Right End | 1 | 0 | 0.0 | 0 | 0 |
| Sum | --- | --- | 430 | 5133 | 11.9 | 3191 | 23 |
| Avg | --- | --- | 3 | 31 | 11.9 | 19 | 0 |