Player - Interceptions
| NameFL | TAbb | PosN | Int | IntY | IntAvg | IntL | IntTDs |
| Roman Harper | ATN | Strong Safety | 8 | 34 | 4.3 | 20 | 0 |
| Josh Bullocks | MNN | 1st Defensive Back | 6 | 106 | 17.7 | 25 | 0 |
| Bryant McFadden | DAN | Right CB | 6 | 58 | 9.7 | 20 | 0 |
| Donte Whitner | NYN | Free Safety | 6 | 56 | 9.3 | 20 | 0 |
| LaRon Landry | NEA | Free Safety | 6 | 54 | 9.0 | 22 | 0 |
| Danieal Manning | DEN | 1st Defensive Back | 6 | 46 | 7.7 | 20 | 0 |
| Ken Hamlin | KCA | Free Safety | 6 | 43 | 7.2 | 13 | 0 |
| Bryan Scott | DEN | Strong Safety | 5 | 85 | 17.0 | 25 | 0 |
| Cortland Finnegan | SFN | Right CB | 5 | 76 | 15.2 | 54 | 1 |
| Walt Harris | MNN | Right CB | 5 | 72 | 14.4 | 25 | 0 |
| Domonique Foxworth | BAA | Left CB | 5 | 69 | 13.8 | 25 | 0 |
| Jermaine Phillips | JXA | Strong Safety | 5 | 52 | 10.4 | 25 | 0 |
| Terrence McGee | SDA | Left CB | 5 | 40 | 8.0 | 25 | 0 |
| Samari Rolle | SEN | Left CB | 5 | 32 | 6.4 | 22 | 0 |
| Tanard Jackson | NON | Free Safety | 5 | 24 | 4.8 | 10 | 0 |
| Phillip Buchanon | HOA | Left CB | 5 | 24 | 4.8 | 20 | 0 |
| Abram Elam | MNN | Strong Safety | 5 | 19 | 3.8 | 10 | 1 |
| Sheldon Brown | ATN | Right CB | 4 | 87 | 21.8 | 77 | 1 |
| Michael Griffin | HOA | Free Safety | 4 | 85 | 21.3 | 25 | 0 |
| Chris Gamble | TNA | Left CB | 4 | 72 | 18.0 | 50 | 1 |
| Brandon Meriweather | PIA | Strong Safety | 4 | 57 | 14.3 | 25 | 0 |
| Nick Harper | JXA | Left CB | 4 | 45 | 11.3 | 20 | 0 |
| Ty Law | OAA | Right CB | 4 | 45 | 11.3 | 25 | 0 |
| Brent Grimes | PIA | 1st Defensive Back | 4 | 36 | 9.0 | 20 | 0 |
| Shawn Springs | NYA | Left CB | 4 | 36 | 9.0 | 22 | 0 |
| Brandon Flowers | KCA | Right CB | 4 | 20 | 5.0 | 20 | 0 |
| Chris Houston | NON | Right CB | 4 | 18 | 4.5 | 10 | 0 |
| Renaldo Hill | JXA | Free Safety | 4 | 12 | 3.0 | 12 | 0 |
| Gibril Wilson | BFA | Strong Safety | 3 | 126 | 42.0 | 72 | 3 |
| Gerald Sensabaugh | DAN | Strong Safety | 3 | 101 | 33.7 | 79 | 1 |
| Tyrell Johnson | OAA | 1st Defensive Back | 3 | 93 | 31.0 | 64 | 1 |
| Nate Clements | ATN | Left CB | 3 | 80 | 26.7 | 36 | 1 |
| Charles Woodson | OAA | Left CB | 3 | 42 | 14.0 | 20 | 0 |
| Antoine Bethea | GBN | Free Safety | 3 | 38 | 12.7 | 22 | 0 |
| Quintin Mikell | TNA | Strong Safety | 3 | 38 | 12.7 | 25 | 0 |
| Brandon Carr | PIA | Left CB | 3 | 37 | 12.3 | 13 | 0 |
| Eric Weddle | SFN | Free Safety | 3 | 34 | 11.3 | 22 | 0 |
| Reggie Nelson | SLN | Free Safety | 3 | 32 | 10.7 | 20 | 0 |
| David Thornton | SFN | Left LB | 3 | 32 | 10.7 | 20 | 1 |
| James Sanders | TBN | Free Safety | 3 | 27 | 9.0 | 15 | 0 |
| D. Rodgers-Cromart | PIA | Right CB | 3 | 26 | 8.7 | 13 | 0 |
| Deshea Townsend | NON | 1st Defensive Back | 3 | 26 | 8.7 | 22 | 0 |
| Ronde Barber | TBN | Right CB | 3 | 23 | 7.7 | 13 | 0 |
| Stanford Routt | TBN | 1st Defensive Back | 3 | 19 | 6.3 | 15 | 0 |
| Andre' Goodman | PHN | Right CB | 3 | 12 | 4.0 | 12 | 0 |
| Brian Dawkins | SDA | Free Safety | 3 | 0 | 0.0 | 0 | 0 |
| Chris Horton | SEN | Strong Safety | 3 | 0 | 0.0 | 0 | 0 |
| Antonio Cromartie | NYN | Right CB | 2 | 90 | 45.0 | 90 | 1 |
| Ernie Sims | HOA | Right LB | 2 | 50 | 25.0 | 37 | 1 |
| Anthony Henry | DAN | Right CB | 2 | 45 | 22.5 | 25 | 0 |
| Matt Roth | NYA | Left O LB | 2 | 40 | 20.0 | 40 | 1 |
| Will A. Allen | GBN | 1st Defensive Back | 2 | 36 | 18.0 | 25 | 1 |
| Rashean Mathis | SLN | Left CB | 2 | 35 | 17.5 | 22 | 0 |
| Marcus Trufant | BFA | Left CB | 2 | 35 | 17.5 | 20 | 0 |
| Kenny Phillips | CHN | 1st Defensive Back | 2 | 35 | 17.5 | 22 | 0 |
| Kerry Rhodes | BAA | Free Safety | 2 | 34 | 17.0 | 22 | 0 |
| Charles Godfrey | PHN | Free Safety | 2 | 29 | 14.5 | 25 | 0 |
| Quentin Jammer | HOA | Left CB | 2 | 25 | 12.5 | 25 | 0 |
| Ken Lucas | TNA | Right CB | 2 | 25 | 12.5 | 15 | 0 |
| David Barrett | PHN | 1st Defensive Back | 2 | 24 | 12.0 | 20 | 0 |
| Ralph Brown | KCA | 1st Defensive Back | 2 | 19 | 9.5 | 15 | 0 |
| Yeremiah Bell | TNA | Strong Safety | 2 | 17 | 8.5 | 13 | 0 |
| David Harris | TNA | Right I LB | 2 | 16 | 8.0 | 12 | 0 |
| Kawika Mitchell | CHN | Left LB | 2 | 16 | 8.0 | 12 | 0 |
| Asante Samuel | SLN | Left CB | 2 | 15 | 7.5 | 15 | 0 |
| Chris Hope | SFN | Strong Safety | 2 | 15 | 7.5 | 15 | 0 |
| Fred Bennett | KCA | 1st Defensive Back | 2 | 15 | 7.5 | 15 | 0 |
| Leon Hall | DEN | Right CB | 2 | 14 | 7.0 | 10 | 0 |
| Madieu Williams | SDA | Free Safety | 2 | 13 | 6.5 | 13 | 0 |
| Terence Newman | GBN | Left CB | 2 | 13 | 6.5 | 13 | 0 |
| Will Allen | JXA | Left CB | 2 | 12 | 6.0 | 12 | 0 |
| Michael Huff | CHN | 1st Defensive Back | 2 | 12 | 6.0 | 12 | 0 |
| Thomas Davis | CHN | Right LB | 2 | 11 | 5.5 | 11 | 1 |
| Kevin Dockery | DAN | 1st Defensive Back | 2 | 4 | 2.0 | 4 | 0 |
| D'Qwell Jackson | DAN | Right I LB | 2 | 4 | 2.0 | 4 | 0 |
| Isaac Sopoaga | MNN | Left End | 2 | 4 | 2.0 | 4 | 0 |
| Champ Bailey | CHN | Left CB | 2 | 4 | 2.0 | 4 | 0 |
| Sean Jones | SDA | Strong Safety | 2 | 0 | 0.0 | 0 | 0 |
| Adrian Wilson | SEN | Strong Safety | 2 | 0 | 0.0 | 0 | 0 |
| Nick Collins | NON | Free Safety | 2 | 0 | 0.0 | 0 | 0 |
| Deon Grant | BFA | Strong Safety | 2 | 0 | 0.0 | 0 | 0 |
| Jacob Ford | TNA | Def End | 1 | 64 | 64.0 | 64 | 1 |
| Jared Allen | BFA | Right End | 1 | 54 | 54.0 | 54 | 1 |
| Adalius Thomas | BAA | Right O LB | 1 | 50 | 50.0 | 50 | 1 |
| Bryan Thomas | PIA | Left O LB | 1 | 31 | 31.0 | 31 | 1 |
| Kenyon Coleman | PHN | Right End | 1 | 25 | 25.0 | 25 | 0 |
| Ronald Bartell | SEN | Left CB | 1 | 25 | 25.0 | 25 | 0 |
| Kevin Payne | CHN | Strong Safety | 1 | 25 | 25.0 | 25 | 0 |
| Alex Brown | DEN | Right End | 1 | 25 | 25.0 | 25 | 1 |
| Juqua Parker | GBN | Left End | 1 | 25 | 25.0 | 25 | 0 |
| Chevis Jackson | SLN | 1st Defensive Back | 1 | 22 | 22.0 | 22 | 0 |
| Lance Briggs | TBN | Right LB | 1 | 22 | 22.0 | 22 | 0 |
| Jarrett Bush | JXA | 1st Defensive Back | 1 | 22 | 22.0 | 22 | 0 |
| Courtney Brown | DEN | 1st Defensive Back | 1 | 22 | 22.0 | 22 | 0 |
| Tedy Bruschi | NYN | Right I LB | 1 | 21 | 21.0 | 21 | 1 |
| Dunta Robinson | BFA | Right CB | 1 | 20 | 20.0 | 20 | 0 |
| Paul Oliver | HOA | 1st Defensive Back | 1 | 20 | 20.0 | 20 | 0 |
| Dre' Bly | DEN | Right CB | 1 | 20 | 20.0 | 20 | 0 |
| Nathan Vasher | ATN | Right CB | 1 | 20 | 20.0 | 20 | 0 |
| Jarret Johnson | GBN | Left O LB | 1 | 20 | 20.0 | 20 | 0 |
| Ryan Clark | KCA | Free Safety | 1 | 20 | 20.0 | 20 | 0 |
| Clinton Hart | DAN | Strong Safety | 1 | 20 | 20.0 | 20 | 0 |
| Johnathan Joseph | TBN | Left CB | 1 | 15 | 15.0 | 15 | 0 |
| Aaron Ross | NEA | Left CB | 1 | 13 | 13.0 | 13 | 0 |
| Jamie Winborn | NEA | Left LB | 1 | 13 | 13.0 | 13 | 0 |
| LaMarr Woodley | DAN | Left O LB | 1 | 13 | 13.0 | 13 | 0 |
| Nick Barnett | SLN | Middle LB | 1 | 13 | 13.0 | 13 | 0 |
| Richard Marshall | HOA | 1st Defensive Back | 1 | 13 | 13.0 | 13 | 0 |
| Jason Ferguson | NEA | Nose Tackle | 1 | 13 | 13.0 | 13 | 0 |
| Lofa Tatupu | NYA | Middle LB | 1 | 13 | 13.0 | 13 | 0 |
| Clint Ingram | OAA | Left LB | 1 | 13 | 13.0 | 13 | 0 |
| Jordan Babineaux | CHN | 1st Defensive Back | 1 | 12 | 12.0 | 12 | 0 |
| Pisa Tinoisamoa | NEA | Right LB | 1 | 12 | 12.0 | 12 | 0 |
| Antoine Winfield | SDA | Left CB | 1 | 12 | 12.0 | 12 | 0 |
| Jason Taylor | DEN | Def End | 1 | 12 | 12.0 | 12 | 0 |
| Ben Leber | PHN | Right LB | 1 | 12 | 12.0 | 12 | 0 |
| Leigh Bodden | JXA | Right CB | 1 | 12 | 12.0 | 12 | 0 |
| Chike Okeafor | BAA | Left LB | 1 | 12 | 12.0 | 12 | 0 |
| Randall Gay | BAA | Left CB | 1 | 12 | 12.0 | 12 | 0 |
| Bradie James | TBN | Left I LB | 1 | 12 | 12.0 | 12 | 0 |
| Antrel Rolle | BAA | Free Safety | 1 | 12 | 12.0 | 12 | 0 |
| Cato June | NON | Left LB | 1 | 12 | 12.0 | 12 | 0 |
| Mike Brown | CHN | Free Safety | 1 | 12 | 12.0 | 12 | 0 |
| Ellis Hobbs | MNN | Right CB | 1 | 10 | 10.0 | 10 | 0 |
| Nick Roach | JXA | Left LB | 1 | 10 | 10.0 | 10 | 0 |
| Kirk Morrison | SFN | Middle LB | 1 | 6 | 6.0 | 6 | 1 |
| Kris Jenkins | SFN | Nose Tackle | 1 | 4 | 4.0 | 4 | 0 |
| Willie McGinest | DAN | Left O LB | 1 | 4 | 4.0 | 4 | 0 |
| Calvin Pace | JXA | Right O LB | 1 | 4 | 4.0 | 4 | 0 |
| Daryl Smith | KCA | Middle LB | 1 | 4 | 4.0 | 4 | 0 |
| Chad Greenway | NYA | Left LB | 1 | 4 | 4.0 | 4 | 0 |
| Vincent Fuller | OAA | 1st Defensive Back | 1 | 4 | 4.0 | 4 | 0 |
| Marlon McCree | OAA | Free Safety | 1 | 4 | 4.0 | 4 | 0 |
| Brian Witherspoon | OAA | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Melvin Bullitt | KCA | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Derrick Brooks | GBN | Right LB | 1 | 0 | 0.0 | 0 | 0 |
| Bob Sanders | GBN | Strong Safety | 1 | 0 | 0.0 | 0 | 0 |
| O.J. Atogwe | NYA | Free Safety | 1 | 0 | 0.0 | 0 | 0 |
| Charles Tillman | NYA | Left CB | 1 | 0 | 0.0 | 0 | 0 |
| Jacques Reeves | NEA | Left CB | 1 | 0 | 0.0 | 0 | 0 |
| A.J. Hawk | CHN | Right LB | 1 | 0 | 0.0 | 0 | 0 |
| Tramon Williams | NYN | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Chinedum Ndukwe | DAN | Strong Safety | 1 | 0 | 0.0 | 0 | 0 |
| Sabby Piscitelli | SFN | 1st Defensive Back | 1 | 0 | 0.0 | 0 | 0 |
| Marvin White | SEN | Free Safety | 1 | 0 | 0.0 | 0 | 0 |
| James Harrison | BFA | Right O LB | 1 | 0 | 0.0 | 0 | 0 |
| Kelvin Hayden | TBN | Left CB | 1 | 0 | 0.0 | 0 | 0 |
| Akeem Jordan | SEN | Right LB | 1 | 0 | 0.0 | 0 | 0 |
| Darrelle Revis | BAA | Left CB | 1 | 0 | 0.0 | 0 | 0 |
| Julian Peterson | SEN | Right LB | 1 | 0 | 0.0 | 0 | 0 |
| DeMarcus Ware | BFA | Right O LB | 1 | 0 | 0.0 | 0 | 0 |
| Jevon Kearse | SEN | Left End | 1 | 0 | 0.0 | 0 | 0 |
| Sum | --- | --- | 334 | 3786 | 11.3 | 2632 | 23 |
| Avg | --- | --- | 2 | 25 | 11.3 | 17 | 0 |